To respond to the threats posed by Illicit Financial Flows (IFFs) from the African continent, the African Union Commission (AUC) jointly with the United Nations Economic Commission for Africa (UNECA) established a High-level panel on Illicit Financial Flows from Africa chaired by Thabo Mbeki. The panel was tasked with studying continent specific challenges from IFFs and develops recommendations to curb the phenomenon. The report whose recommendations have since been adopted by all Heads of State and Government in Africa. The adoption represents a major milestone in the continent’s efforts to curb IFFs. This milestone has provided an impetus for policy engagement at continental level. The strategic driver under this thematic programme is flawed global tax and financial architecture that leads to IFFs. This is worsened by the lack of a global representative body to reform the system. Our goal is to achieve an inclusive and transparent global regulatory financial framework with a governance structure that curbs Illicit Financial Flows.